I think it's him being a darn good quarterback. I can't say enough to be on this team and be thankful to have him as a quarterback. The Colts defense, one of the friendliest units in the league last year (Ranked 28th in total D), is a work in progress.Indianapolis DT Fili Moala helps the defense immediately, but the player to focus on is RB Donald Brown. Brown quietly lead the NCAA in rushing yards in 2008 and will step in right away for the Colts. Joseph Addai is still the number 1 running back, but has proven to be injuryprone, so Brown will get reps right away to minimize Addai's touches.

Tamara Vyshkina1 and Bernadette Kalman1,2Received 12 March 2008; Revised 21 April 2008; Accepted 25 April 2008; Published online 2 June 2008.Top of pageAbstractNeurodegeneration develops in association with inflammation and demyelination in multiple sclerosis. Available data suggest that the progressive neuroaxonal loss begins in the earliest stages of the disease and underlies the ac